Screening with an NMNAT2-MSD platform identifies small molecules that modulate NMNAT2 levels in cortical neurons

Yousuf O. Ali, Gillian Bradley, Hui-Chen Lu
Publication Date
March 7, 2017
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The study identified 24 compounds -- including caffeine -- with the potential to boost an enzyme in the brain shown to protect against dementia.

Citation

Ali, Y. O. et al. Screening with an NMNAT2-MSD platform identifies small molecules that modulate NMNAT2 levels in cortical neurons. Sci. Rep. 7, 43846; doi: 10.1038/srep43846 (2017).